Gadolinium Contract Dye and Nephrogenic System Fibrosis
Persons with kidney problems should avoid any dyes with Gadolinium and should be aware of this potential danger if they are having an MRI or MRA done. Nephrogenic systemic fibrosis (NSF) or Nephrogenic fibrosing dermopathy is a rare and serious syndrome that involves fibrosis of skin, joints, eyes, and internal organs. Scientific research has recently discovered an association between nephrogenic system fibrosis with exposure to gadolinium in patients with severe kidney failure.
In NSF, patients develop large areas of hardened skin with fibrotic nodules and plaques. Flexion contractures with an accompanying limitation of range of motion can also occur. NSF resembles scleromyxedema at the histologic (microscopic) level; it shows a proliferation of dermal fibroblasts and dendritic cells, thickened collagen bundles, increased elastic fibers, and deposits of mucin.
People that have had MRIs and are having unexplained symptoms including skin hardening, fibrotic nodules, strange lesions, deep pain, joint pain, and inability to walk or use of their joints, should contact their doctors to determine if they have Nephrogenic systemic fibrosis (NSF), Nephrogenic fibrosing dermopathy, or renal insufficiency.
For more information on Nephrogenic Systemic Fibrosis or a potential Nephrogenic Systemic Fibrosis law suit, feel free to go to the following web page Nephrogenic System Fibrosis and MRI Contrast Dye Lawsuits.